Participate in TMPRSS3 Research
Get involved with Transmembrane Serine Protease 3/ TMPRSS3 hearing loss research.
If you know of more research studies, submit them below.
DO YOU WANT TO HELP TMPRSS3 GENE RESEARCH?
Turn your own skin cells into stem cells. If you have a confirmed diagnosis of TMPRSS3-related hearing loss, Dr. Rick Nelson has developed a process of taking human tissue and turning it into stem cells. These stem cells can be used to make "inner ear organoids", which have sensory cells similar to the human cochlea. These organoids can help understand how the gene causes hearing loss. His lab is currently doing similar research with mice that also have a mutation.
This research would require an in-person visit to the University of Indiana and a small 3-mm skin biopsy.
Contact Dr Rick Nelson, Associate Professor of Otolaryngology-Head & Neck Surgery, Indiana University School of Medicine, Indianapolis, IN. Email firstname.lastname@example.org for more information.
Do you have a confirmed diagnosis of hereditary hearing loss due to pathogenic variants in the TMPRSS3 gene? Send us a note.
With your help and connection we can keep developing resources to help understand and potentially treat DFNB8/10 hearing loss.
New gene therapies and precision medicine approaches to hearing loss are in the works. With better diagnostics and a potential genetic newborn hearing screening, this field is changing rapidly.
When we discover exciting new research and possibilities, we'll post it here.
Email us at TMPRSS3@gmail.com.